Analyzing the research trends of COVID-19 using topic modeling approach

PurposeThe COVID-19 pandemic has impacted 222 countries across the globe, with millions of people losing their lives. The threat from the virus may be assessed from the fact that most countries across the world have been forced to order partial or complete shutdown of their economies for a period of time to contain the spread of the virus. The fallout of this action manifested in loss of livelihood, migration of the labor force and severe impact on mental health due to the long duration of confinement to homes or residences.Design/methodology/approachThe current study identifies the focus areas of the research conducted on the COVID-19 pandemic. s of papers on the subject were collated from the SCOPUS database for the period December 2019 to June 2020. The collected sample data (after preprocessing) was analyzed using Topic Modeling with Latent Dirichlet Allocation.FindingsBased on the research papers published within the mentioned timeframe, the study identifies the 10 most prominent topics that formed the area of interest for the COVID-19 pandemic research.Originality/valueWhile similar studies exist, no other work has used topic modeling to comprehensively analyze the COVID-19 literature by considering diverse fields and domains.

Identification Symptoms and Underlying Diseases Related to COVID-19 And Prediction of Death Status Using Artificial Neural Network and Logistic Regression: A Data Mining Approach.

Background and Objectives: Due to the high prevalence of COVID-19 disease and its high mortality rate, it is necessary to identify the symptoms, demographic information and underlying diseases that effectively predict COVID-19 death. Therefore, in this study, we aimed to predict the mortality behavior due to COVID-19 in Khorasan Razavi province. Method(s): This study collected data from 51, 460 patients admitted to the hospitals of Khorasan Razavi province from 25 March 2017 to 12 September 2014. Logistic regression and Neural network methods, including machine learning methods, were used to identify survivors and non-survivors caused by COVID-19. Result(s): Decreased consciousness, cough, PO2 level less than 93%, age, cancer, chronic kidney diseases, fever, headache, smoking status, and chronic blood diseases are the most important predictors of death. The accuracy of the artificial neural network model was 89.90% in the test phase. Also, the sensitivity, specificity and area under the rock curve in this model are equal to 76.14%, 91.99% and 77.65%, respectively. Conclusion(s): Our findings highlight the importance of some demographic information, underlying diseases, and clinical signs in predicting survivors and non-survivors of COVID-19. Also, the neural network model provided high accuracy in prediction. However, medical research in this field will lead to complementary results by using other methods of machine learning and their high power.Copyright © 2022 The Authors.

Integrating deep learning algorithms for the lung segmentation and body-part-specific anatomical classification with Medical Imaging and Data Resource Center (MIDRC)

Medical Imaging and Data Resource Center (MIDRC) has been built to support AI-based research in response to the COVID-19 pandemic. One of the main goals of MIDRC is to make data collected in the repository ready for AI analysis. Due to data heterogeneity, there is a need to standardize data and make data-mining easier. Our study aims to stratify imaging data according to underlying anatomy using open-source image processing tools. The experiments were performed using Google Colaboratory on computed tomography (CT) imaging data available from the MIDRC. We adopted the existing open-source tools to process CT series (N=389) to define the image sub-volumes according to body part classification, and additionally identified series slices containing specific anatomic landmarks. Cases with automatically identified chest regions (N=369) were then processed to automatically segment the lungs. In order to assess the accuracy of segmentation, we performed outlier analysis using 3D shape radiomics features extracted from the left and right lungs. Standardized DICOM objects were created to store the resulting segmentations, regions, landmarks and radiomics features. We demonstrated that the MIDRC chest CT collections can be enriched using open-source analysis tools and that data available in MIDRC can be further used to evaluate the robustness of publicly available tools. © 2023 SPIE.

HarDNet and Dual-Code Attention Mechanism based model for medical images segmentation

During the formation of medical images, they are easily disturbed by factors such as acquisition devices and tissue backgrounds, causing problems such as blurred image backgrounds and difficulty in differentiation. In this paper, we combine the HarDNet module and the multi-coding attention mechanism module to optimize the two stages of encoding and decoding to improve the model segmentation performance. In the encoding stage, the HarDNet module extracts medical image feature information to improve the segmentation network operation speed. In the decoding stage, the multi-coding attention module is used to extract both the position feature information and channel feature information of the image to improve the model segmentation effect. Finally, to improve the segmentation accuracy of small targets, the use of Cross Entropy and Dice combination function is proposed as the loss function of this algorithm. The algorithm has experimented on three different types of medical datasets, Kvasir-SEG, ISIC2018, and COVID-19CT. The values of JS were 0.7189, 0.7702, 0.9895, ACC were 0.8964, 0.9491, 0.9965, SENS were 0.7634, 0.8204, 0.9976, PRE were 0.9214, 0.9504, 0.9931. The experimental results showed that the model proposed in this paper achieved excellent segmentation results in all the above evaluation indexes, which can effectively assist doctors to diagnose related diseases quickly and improve the speed of diagnosis and patients’quality of life. Author

ASSOCIATION RULE MINING FOR PREDICTION OF COVID-19

COVID-19 is a raging pandemic that has created havoc with its impact ranging from loss of millions of human lives to social and economic disruptions of the entire world. Therefore, error-free prediction, quick diagnosis, disease identification, isolation and treatment of a COVID patient have become extremely important. Nowadays, mining knowledge and providing scientific decision making for diagnosis of diseases from clinical datasets has found wide-ranging applications in healthcare sector. In this direction, among different data mining tools, association rule mining has already emerged out as a popular technique to extract invaluable information and develop important knowledge-base to help in intelligent diagnosis of distinct diseases quickly and automatically. In this paper, based on 5434 records of COVID cases collected from a popular data science community and using Rapid Miner Studio software, an attempt is put forward to develop a predictive model based on frequent pattern growth algorithm of association rule mining to determine the likelihood of COVID-19 in a patient. It identifies breathing problem, fever, dry cough, sore throat, abroad travel and attended large gathering as the main indicators of COVID-19. Employing the same clinical dataset, a linear regression model is also proposed having a moderately high coefficient of determination of 0.739 in accurately predicting the occurrence of COVID-19. A decision support system can also be developed using the association rules to ease out and automate early detection of other diseases. © 2023 by the authors.

Text Mining and Emotion Classification on Monkeypox Twitter Dataset: A Deep Learning-Natural Language Processing (NLP) Approach

Emotion classification has become a valuable tool in analyzing text and emotions people express in response to events or crises, particularly on social media and other online platforms. The recent news about monkeypox highlighted various emotions individuals felt during the outbreak. People’s opinions and concerns have been very different based on their awareness and understanding of the disease. Although there have been studies on monkeypox, emotion classification related to this virus has not been considered. As a result, this study aims to analyze the emotions individual expressed on social media posts related to the monkeypox disease. Our goal is to provide real-time information and identify critical concerns about the disease. To conduct our analysis, first, we extract and preprocess 800,000 datasets and then use NRCLexicon, a Python library, to predict and measure the emotional significance of each text. Secondly, we develop deep learning models based on Convolutional Neural Networks (CNN), Long Short-Term Memory (LSTM), Bidirectional LSTM (BiLSTM), and the combination of Convolutional Neural Networks and Long Short-Term Memory (CLSTM) for emotion classification. We use SMOTE (Synthetic Minority Oversampling Technique) and Random Undersampling techniques to address the class imbalance in our training dataset. The results of our study revealed that the CNN model achieved the highest performance with an accuracy of 96%. Overall, emotion classification on the monkeypox dataset can be a powerful tool for improving our understanding of the disease. The findings of this study will help develop effective interventions and improve public health. Author

DIAGNOSIS OF MEDICAL CONDITIONS IN PATIENTS USING MACHINE LEARNING MODELS

A variety of patient care and intelligent health systems can benefit from the implementation of artificial intelligence as a tool to aid caregivers. Machine learning and deep learning are two types of AI that are increasingly being used in the medical industry. Artificial intelligence methods require a large amount of clinical data from a range of imaging modalities for correct disease diagnosis. In addition, AI has greatly enhanced the quality of hospital stays, allowing patients to be released sooner and complete their recoveries at home. This article aims to provide the information on the field of AI subset i.e., machine learning-based disease detection with information that will aid them in making better decision making. This helps the researchers to classify the medical conditions in patients with a prominent dataset.

Contextual Market Basket Analysis during Covid-19

One form of Data Mining application to analyze Market Basket Analysis. Market Basket Analysis helps identify buying patterns formed from concurrent transactions. One of the problems with Market Basket Analysis is that customer needs vary according to season and time of day, especially during this covid-19 season. For this purpose, by using the Artificial Neural Network (ANN) Approach that is connected to Market Basket Analysis, it can analyze and compare purchasing patterns and can identify rules that were formed before and after covid-19;several rule changes were found due to changes in people's behavior patterns. [ FROM AUTHOR] Copyright of Journal of Social Science (2720-9938) is the property of Ridwan Institute and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)

An optimisation approach for determining the efficiency of vital medical devices in intensive care units with COVID-19 patients using Apriori algorithm

Improving the process of strategic management in hospitals preparation and equipping the intensive care units (ICUs) and the availability of medical devices plays an important role for knowing consumer behaviour and need. This cross-sectional study was performed in the ICU of Farhikhtegan Hospital, Tehran, Iran for a period of six months. During these months, ten medical devices have been used 5,497 times. These devices include: ventilator, oxygen cylinder, infusion pump, electrocardiography machine, vital signs monitor, oxygen flowmeter, wavy mattress, ultrasound sonography machine, ultrasound echocardiography machine, and dialysis machine. The Apriori algorithm showed that four devices: ventilator, oxygen cylinder, vital signs monitoring device, oxygen flowmeter are the most used ones by patients. These devices are positively correlated with each other and their confidence is over 80% and their support is 73%. For validating the results, we have used equivalence class clustering and bottom-up lattice traversal (ECLAT) algorithm in our dataset.

Mining association rules for classification using frequent generator itemsets in arules package

Mining frequent itemsets is an attractive research activity in data mining whose main aim is to provide useful relationships among data. Consequently, several open-source development platforms are continuously developed to facilitate the users' exploitation of new data mining tasks. Among these platforms, the R language is one of the most popular tools. In this paper, we propose an extension of arules package by adding the option of mining frequent generator itemsets. We discuss in detail how generators can be used for a classification task through an application example in relation with COVID-19.

Current status and hotspot of Lonicera Japonica Flos research based on bibliometrics.

In order to comprehensively understand the research hotspots and development trends of Lonicera Japonica Flos in the past 20 years, and to provide intuitive data reference and objective opinions and suggestions for subsequent related research in this field, this study collected 8 871 Chinese literature and 311 English literature related to Lonicera Japonica Flos research in the core collection databases of Wanfang Data), CNKI and Web of Science (WOS) from 2002 to 2021, and conducted bibliometric and visual analysis using vosviewer. The results showed that the research on the active components of Lonicera Japonica Flos based on phenolic acid components, the research on the mechanism of novel coronavirus pneumonia based on data mining and molecular docking technology, and the pharmacological research on the anti-inflammatory and antiviral properties of Lonicera Japonica Flos are the three hot research directions in the may become the future research direction. In this paper, we analyze the research on Lonicera Japonica Flos from five aspects: active ingredients, research methods, formulation and preparation, pharmacological effects and clinical applications, aiming to reveal the research hotspots, frontiers and development trends in this field and provide predictions and references for future research.Copyright © Drug Evaluation Research 2022.

Drug discovery for coronavirus disease 2019 based on text mining and biomedical databases.

Objective Based on text mining technology and biomedical database, data mining and analysis of coronavirus disease 2019 (COVID-19) were carried out, and COVID-19 and its main symptoms related to fever, cough and respiratory disorders were explored. Methods The common targets of COVID-19 and its main symptoms cough, fever and respiratory disorder were obtained by GenCLiP 3 website, Gene ontology in metascape database (GO) and pathway enrichment analysis, then STRING database and Cytoscape software were used to construct the protein interaction network of common targets, the core genes were screened and obtained. DGIdb database and Symmap database were used to predict the therapeutic drugs of traditional Chinese and Western medicine for the core genes. Results A total of 28 gene targets of COVID-19 and its main symptoms were obtained, including 16 core genes such as IL2, IL1B and CCL2. Through the screening of DGIdb database, 28 chemicals interacting with 16 key targets were obtained, including thalidomide, leflunomide and cyclosporine et al. And 70 kinds of Chinese meteria medica including Polygonum cuspidatum, Astragalus membranaceus and aloe. Conclusion The pathological mechanism of COVID-19 and its main symptoms may be related to 28 common genes such as CD4, KNG1 and VEGFA, which may participate in the pathological process of COVID-19 by mediating TNF, IL-17 and other signal pathways. Potentially effective drugs may play a role in the treatment of COVID-19 through action related target pathway.Copyright © 2022 Tianjin Press of Chinese Herbal Medicines. All Rights Reserved.

COVID-19 Bed Management Using a Two-Step Process Mining and Discrete-Event Simulation Approach

The sudden admission of many patients with similar needs caused by the COVID-19 (SARS-CoV-2) pandemic forced health care centers to temporarily transform units to respond to the crisis. This process greatly impacted the daily activities of the hospitals. In this paper, we propose a two-step approach based on process mining and discrete-event simulation for sizing a recovery unit dedicated to COVID-19 patients inside a hospital. A decision aid framework is proposed to help hospital managers make crucial decisions, such as hospitalization cancellation and resource sizing, taking into account all units of the hospital. Three sources of patients are considered: (i) planned admissions, (ii) emergent admissions representing day-to-day activities, and (iii) COVID-19 admissions. Hospitalization pathways have been modeled using process mining based on synthetic medico-administrative data, and a generic model of bed transfers between units is proposed as a basis to evaluate the impact of those moves using discrete-event simulation. A practical case study in collaboration with a local hospital is presented to assess the robustness of the approach. Note to Practitioners—In this paper we develop and test a new decision-aid tool dedicated to bed management, taking into account exceptional hospitalization pathways such as COVID-19 patients. The tool enables the creation of a dedicated COVID-19 intensive care unit with specific management rules that are fine-tuned by considering the characteristics of the pandemic. Health practitioners can automatically use medico-administrative data extracted from the information system of the hospital to feed the model. Two execution modes are proposed: (i) fine-tuning of the staffed beds assignment policies through a design of experiment and (ii) simulation of user-defined scenarios. A practical case study in collaboration with a local hospital is presented. The results show that our model was able to find the strategy to minimize the number of transfers and the number of cancellations while maximizing the number of COVID-19 patients taken into care was to transfer beds to the COVID-19 ICU in batches of 12 and to cancel appointed patients using ICU when the department hit a 90% occupation rate. IEEE

WHAT DO USERS OF RHEUMATOID ARTHRITIS ONLINE FORUMS TALK ABOUT? APPLYING A DEEP LEARNING APPROACH TO UNCOVER COMMON THEMES

BackgroundSocial media platforms have become a vital resource for individuals seeking information and support regarding health issues, including rheumatoid arthritis (RA). As such, the content generated on these platforms represents a valuable source of data for gaining insight into patients' perspectives on RA. However, previous research in this area has primarily relied on qualitative analyses of small sample sizes, limiting the ability to extract meaningful insights from social media content related to RA. With the advancement of machine learning techniques, it is now possible to analyze and extract insights from large volumes of social media posts related to RA.ObjectivesThe purpose of this study was to identify the most common topics discussed in a large dataset of submissions about RA on Reddit, one of the world's largest online forums.MethodsThe data for this study was collected from the two largest Reddit forums ("subreddits”) dedicated to RA, r/rheumatoid arthritis and r/rheumatoid, which have 18.9k and 7.6k members respectively. We retrieved all submissions but excluded responses in our analyses. All deleted or duplicate submissions and those with fewer than 10 words were removed, retaining 11,094 submissions from over 5,000 users for the analysis. To identify common themes, we applied topic modeling, a technique in natural language processing that identifies underlying themes or topics in a collection of documents. We used the Bertopic Python package (Grootendorst, 2022), which employs deep learning techniques to perform the topic modeling.ResultsThe data indicates a significant increase in submissions to the two subreddits, rising from 113 in 2014 to 2892 in 2021 and 1928 in the first 8 months of 2022. Upon analysis, 65 topics were identified, with 4162 submissions (37.5%) remaining unclassified. A topic specifically dedicated to requests to participate in surveys was removed as it did not pertain to the experiences of forum users. Among the remaining topics, the top 10 accounted for 44.90% of all submissions. To better understand each topic, a sample of 10 submissions with the highest probability for that topic were examined (Table 1).Table 1.Top 10 most frequent topicsTopicn of submissionsShare of total*Side effects of methotrexate5268.02%COVID & vaccines4627.04%Mental health4386.68%RF and anti CCP test results3315.04%RA of friends, partners, and close relatives2623.99%Complaints about rheumatologist2123.23%Questions about Humira1882.87%Questions about prednisone1822.77%Diets and RA1752.67%Early symptoms of possible RA1702.59%Exercise and RA1682.56%* After excluding unclassified topicsThree of the ten topics pertained to specific medications - methotrexate, Humira, and prednisone, accounting for 12.71% of the total. The most prevalent topic, at 8.02%, focused on the side effects of methotrexate, with many submissions inquiring about symptoms such as nausea. The second most common topic, at 7.04%, primarily revolved around COVID-19 and related issues, with some pre-COVID vaccine discussions also included. In 2021, COVID-related discussions were the most prevalent topic. The third most frequent topic (6.68% of total), dealt with mental health and the emotional struggles faced by those living with RA.ConclusionThe surge in submissions on Reddit demonstrates its growing popularity as an online forum for discussing topics related to RA. Utilizing deep learning-based topic modeling has proven to be an effective method for extracting meaningful topics from the questions and experiences shared by users. The vast amount of data generated by Reddit, in combination with advanced machine learning techniques, enables both an overview of the various topics discussed and a detailed examination of specific topics. This makes the use of social media data a valuable source of insight into the concerns of RA platform users.Reference[1]Grootendorst, M. (2022). BERTopic: Neural topic modeling with a class-based TF-IDF procedure. arXiv preprint arXiv:2203.05794.Acknowledgements:NIL.Disclosure of InterestsNone Decla ed.

A Predictive Model for Assessing Satisfaction with Online Learning for Higher Education Students During and After COVID-19 Using Data Mining and Machine Learning Techniques: A Case of Jordanian Institutions

Higher education institutions confronted an escalating unexpected pressure to rapidly transform throughout and after the COVID-19 pandemic, by replacing most of the traditional teaching practices with online-based education. Such transformation required institutions to frequently strive for qualities that meet conceptual requirements of traditional education due to its agility and flexibility. The challenge of such electronic learning styles remains in their potential of bringing out many challenges, along with the advantages it has brought to the educational systems and students alike. This research came to shed the light on several factors presented as a predictive model and proposed to contribute to the success or failure in terms of students' satisfaction with online learning. The study took the kingdom of Jordan as a case example country experiencing online education while and after the covid -19 intensive implementation. The study used a dataset collected from a sample of over "300” students using online questionnaires. The questionnaire included "25” attributes mined into the Knime analytics platform. The data was rigorously learned and evaluated by both the "Decision Tree” and "Naive Bayes” algorithms. Subsequently, results revealed that the decision tree classifier outperformed the naïve bayes in the prediction of student satisfaction, additionally, the existence of the sense of community while learning electronically among other reasons had the most contribution to the satisfaction. Copyright © 2023 by SCITEPRESS - Science and Technology Publications, Lda. Under CC license (CC BY-NC-ND 4.0)

PQSCT: Pseudo-Siamese BERT for Concept Tagging With Both Questions and Solutions

The global outbreak of the new coronavirus epidemic has promoted the development of intelligent education and the utilization of online learning systems. In order to provide students with intelligent services such as cognitive diagnosis and personalized exercises recommendation, a fundamental task is the concept tagging for exercises, which extracts knowledge index structures and knowledge representations for exercises. Unfortunately, to the best of our knowledge, existing tagging approaches based on exercise content either ignore multiple components of exercises, or ignore that exercises may contain multiple concepts. To this end, in this paper, we present a study of concept tagging. First, we propose an improved pre-trained BERT for concept tagging with both questions and solutions (QSCT). Specifically, we design a question-solution prediction task and apply the BERT encoder to combine questions and solutions, ultimately obtaining the final exercise representation through feature augmentation. Then, to further explore the relationship between questions and solutions, we extend the QSCT to a pseudo-siamese BERT for concept tagging with both questions and solutions (PQSCT). We optimize the feature fusion strategy, which integrates five different vector features from local and global into the final exercise representation. Finally, we conduct extensive experiments on real-world datasets, which clearly demonstrate the effectiveness of our proposed models for concept tagging. IEEE

A Validation Study to Confirm the Accuracy of Wearable Devices Based on Health Data Analysis

This research article presents an analysis of health data collected from wearable devices, aiming to uncover the practical applications and implications of such analyses in personalized healthcare. The study explores insights derived from heart rate, sleep patterns, and specific workouts. The findings demonstrate potential applications in personalized health monitoring, fitness optimization, and sleep quality assessment. The analysis focused on the heart rate, sleep patterns, and specific workouts of the respondents. Results indicated that heart rate values during functional strength training fell within the target zone, with variations observed between different types of workouts. Sleep patterns were found to be individualized, with variations in sleep interruptions among respondents. The study also highlighted the impact of individual factors, such as demographics and manually defined information, on workout outcomes. The study acknowledges the challenges posed by the emerging nature of wearable devices and technological constraints. However, it emphasizes the significance of the research, highlighting variations in workout intensities based on heart rate data and the individualized nature of sleep patterns and disruptions. Perhaps the future cognitive healthcare platform may harness these insights to empower individuals in monitoring their health and receiving personalized recommendations for improved well-being. This research opens up new horizons in personalized healthcare, transforming how we approach health monitoring and management.

Systematic computer analysis of the pharmacology of bioflavonoids in the context of increasing the body's antiviral defenses.

Background. The rapidly developing resistance of viruses to synthetic antiviral drugs indicates the need to use substances with multitarget action (to avoid polypharmacy and to improve the safety of treatment). Objective(s): systematic analysis of the scientific literature on the pharmacology of bioflavonoids with an emphasis on their antiviral action. Material and methods. More than 150,000 references of primary sources were found in the PubMed/MEDLINE database of biomedical publications, including 3282 references on the antiviral effects of bioflavonoids. A systematic computerized analysis of this array of publications was carried out in order to identify the main directions in the pharmacology of bioflavonoids with an emphasis on their antiviral, antibacterial and immunomodulatory effects. The literature analysis was carried out using modern methods of topological and metric analysis of big data. Results. The molecular mechanisms of action of baicalin, hesperidin, rutin, quercetin, leukodelphinidin bioflavonoids and epigallocatechin-3gallate, curcumin polyphenols, their anti-inflammatory, antioxidant, antiviral, bactericidal, angioprotective, regenerative effects, and their prospects in therapy, prevention and rehabilitation of patients with COVID-19 and other respiratory viral infections were described in detail. Conclusion. Bioflavonoids and synergistic polyphenols exhibit not only multitarget antiviral effects by inhibiting the main protease, spike proteins, and other target proteins, but also pronounced anti-inflammatory, hepatoprotective, and immunomodulatory effects.Copyright © 2023 Modern Medical Technology. All rights reserved.

Potential Association of Remdesivir and Hyperkalemia: A Disproportionality Analysis in USFDA Adverse Event Reporting System Database

Background: Signal detection is one of the most advanced and promising techniques in the world of pharmacovigilance. Remdesivir is approved for emergency use by the US Food and Drug Administration (FDA) for patients with coronavirus disease 2019 (COVID-19). Its benefit- risk ratio is still being explored because data in the field are rather scant. On the other hand hyperkalemia is a potentially life-threatening electrolyte disorder. Severe hyperkalemia can occur suddenly and can cause life-threatening heart rhythm changes (arrhythmia) that cause a heart attack. Even mild hyperkalemia can cause heart related problems over time if not treated. Objective(s): To evaluate the potential association of Remdesivir with risk of Hyperkalemia by analyzing the spontaneous reports through disproportionality analysis. Method(s): Data were obtained from the public release of data in FAERS. Case/non-case method was adopted for the analysis of association between Remdesivir use and Hyperkalemia. The data-mining algorithm used for the analysis were Reporting Odds Ratio(ROR) and Proportional Reporting Ratio (PRR). A value of ROR-1.96SE>, PRR>=2 were considered as positive signal. Result(s): A total of 7 DE's associated with Remdesivir use and hyperkalemia were reported. The mean age of the patients of Remdesivir associated events was found to be 75 years [95% CI]. The reports by gender were distributed with a male to female ratio of 3:1, though gender was not revealed in 3 reports. The data mining algorithms exhibited positive signal for hyperkalemia (PRR: 2.349, ROR: 2.354) upon analysis as those were well above the pre-set threshold. Three case reports were identified which strengthened these findings and highlighted the importance of laboratory parameters for the early detection of hyperkalemia Conclusion(s): The current study found a potential risk of hyperkalemia with the use of Remdesivir and there is an urgent need to thoroughly investigate the same and take the necessary action to avoid or minimize the risk.Copyright © 2023

A comparison study of topic modeling based literature analysis by using full texts and abstracts of scientific articles: a case of COVID-19 research

PurposeHow to extract useful information from a very large volume of literature is a great challenge for librarians. Topic modeling technique, which is a machine learning algorithm to uncover latent thematic structures from large collections of documents, is a widespread approach in literature analysis, especially with the rapid growth of academic literature. In this paper, a comparison of topic modeling based literature analysis has been done using full texts and s of articles.Design/methodology/approachThe authors conduct a comparison study of topic modeling on full-text paper and corresponding to assess the influence of the different types of documents been used as input for topic modeling. In particular, the authors use the large volumes of COVID-19 research literature as a case study for topic modeling based literature analysis. The authors illustrate the research topics, research trends and topic similarity of COVID-19 research by using Latent Dirichlet allocation (LDA) and topic visualization method.FindingsThe authors found 14 research topics for COVID-19 research. The authors also found that the topic similarity between using full-text paper and corresponding is higher when more documents are analyzed.Originality/valueFirst, this study contributes to the literature analysis approach. The comparison study can help us understand the influence of the different types of documents on the results of topic modeling analysis. Second, the authors present an overview of COVID-19 research by summarizing 14 research topics for it. This automated literature analysis can help specialists in the health and medical domain or other people to quickly grasp the structured morphology of the current studies for COVID-19.